The tie will take place at the Crucial Environmental Stadium on or before Wednesday 15th December, date to be confirmed.
Supporters will be hoping for a repeat of the entertainment served up when the two sides met in the league just four weeks ago when Adam Hinshelwood’s men edged a nine goal thriller at Woodside Road.
The Reds booked their place in round three with what turned out to be a comprehensive win over Seaford Town in the week, thanks in part to a hat-trick from Mo Diallo.
Lewes, who currently sit comfortably in the Isthmian League Premier Division play-off places ,secured their passage to this stage of the competition with 4-1 victory at Littlehampton Town.
The rest of the third round ties are as follows:-
Little Common vs. Three Bridges
Saltdean United vs. Eastbourne Borough
Mile Oak vs. Horsham YMCA
Brighton & Hove Albion vs. Chichester City
Horsham vs. Hastings United
Eastbourne Town vs. Crawley Town
Bexhill United vs. Bognor Regis Town